SLC39A13 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: SLC39A13 Antibody [NBP1-76509] - Immunofluorescence of ZIP13 in human spleen tissue with ZIP13 antibody at 20 ug/mL.

Immunohistochemistry: SLC39A13 Antibody - BSA Free [NBP1-76509] - Immunohistochemistry of SLC39A13 in human spleen tissue with SLC39A13 antibody at 2.5 u/mL.

• Reactivity: Hu
• Applications: ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SLC39A13 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human ZIP13. The immunogen is located within amino acids 150 - 200 of ZIP13. Amino Acid Squence: DSKEEKTSQAPNKD
• Specificity: At least two isoforms of ZIP13 are known to exist; this antibody will detect both isoforms. ZIP13 antibody is predicted to not cross-react with other ZIP family members.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A13
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
• Control Peptide:

  SLC39A13 Peptide (NBP1-76509PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SLC39A13 Antibody - BSA Free

• FLJ25785
• LIV-1 subfamily of ZIP zinc transporter 9
• LZT-Hs9
• solute carrier family 39 (metal ion transporter), member 13
• solute carrier family 39 (zinc transporter), member 13
• Solute carrier family 39 member 13
• zinc transporter ZIP13
• ZIP13
• ZIP-13
• Zrt- and Irt-like protein 13

Background

The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC39A13
• Uniprot:
  • NP_001121697(Human)