Tetanus Toxin Antibody - BSA Free

• Reactivity: Ba
• Applications: ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 5.0 mg/ml

Tetanus Toxin Antibody - BSA Free Summary

• Immunogen: Synthetic peptide corresponding to the amino acids 1300 - 1314 of the native molecule conjugated to Keyhole limpet Haemocyanin
• Specificity: This product recognizes the tetanus toxin, a neurotoxin that inhibits neurotransmitter release.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TETX
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 5.0 mg/ml
• Purity: Protein G purified

Alternate Names for Tetanus Toxin Antibody - BSA Free

• Tentoxylysin

Background

Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TETX