TIM-1/KIM-1/HAVCR Antibody (202)

Immunohistochemistry-Paraffin: TIM-1/KIM-1/HAVCR Antibody (202) [NBP2-90823] - Immunochemical staining of Canine KIM1 in canine kidney with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Product Discontinued

TIM-1/KIM-1/HAVCR Antibody (202) Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Canine TIM-1/KIM-1/HAVCR extracellular domain (XP_854888.1; Tyr 21-Ser 160).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: HAVCR1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:5000-1:10000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:1000-1:4000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for TIM-1/KIM-1/HAVCR Antibody (202)

• CD365
• HAVCR1
• HAVCR-1
• HAVCRT cell immunoglobin domain and mucin domain protein 1
• hepatitis A virus cellular receptor 1
• Kidney injury molecule 1
• KIM1
• KIM-1
• T-cell immunoglobulin and mucin domain-containing protein 1
• TIM1
• TIM-1
• TIM-1TIM
• TIM1TIMD-1
• TIMD1T-cell membrane protein 1

Background

TIM 1 is a transmembrane protein containing immunoglobulin domain and mucin-like domain; it is developmentally expressed at very high levels in the blastocyst. TIM 1 binds hepatitis virus in humans and is expressed on activated CD4+ lymphocytes especially on Th2 cells and has been implicated to play a critical role in the development of atopic disease (in particular airway hyperreactivity) and other Th2-biased immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HAVCR1