ACADVL Antibody - BSA Free

Western Blot: ACADVL Antibody [NBP1-89286] - Analysis using Anti-ACADVL antibody NBP1-89286 (A) shows similar pattern to independent antibody NBP1-89287 (B).

Immunohistochemistry-Paraffin: ACADVL Antibody [NBP1-89286] - Staining of human lymph node shows only weak ctyoplasmic postivity in a subset of non-germinal center of cells.

Immunohistochemistry-Paraffin: ACADVL Antibody [NBP1-89286] - Analysis in human duodenum and lymph node tissues. Corresponding ACADVL RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: ACADVL Antibody [NBP1-89286] - Staining of human duodenum, kidney, lymph node and placenta using Anti-ACADVL antibody NBP1-89286 (A) shows similar protein distribution across tissues to independent antibody NBP1-89287 (B).

Immunohistochemistry-Paraffin: ACADVL Antibody [NBP1-89286] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: ACADVL Antibody [NBP1-89286] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

Immunohistochemistry-Paraffin: ACADVL Antibody [NBP1-89286] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ACADVL Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: VFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQI
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ACADVL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  ACADVL Recombinant Protein Antigen (NBP1-89286PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (85%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ACADVL Antibody - BSA Free

• ACAD6
• acyl-CoA dehydrogenase, very long chain
• acyl-Coenzyme A dehydrogenase, very long chain
• EC 1.3.99
• EC 1.3.99.-
• LCACD
• very long-chain specific acyl-CoA dehydrogenase, mitochondrial
• VLCAD

Background

ACADVL is encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACADVL