CBR4 Antibody - BSA Free

Western Blot: CBR4 Antibody [NBP2-15734] - Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE gel, diluted at 1:1000.

Immunohistochemistry-Paraffin: CBR4 Antibody [NBP2-15734] - Sample: Paraffin-embedded lung carcinoma. CBR4 antibody dilution: 1:250.

• Reactivity: Hu, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CBR4 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CBR4. The exact sequence is proprietary.
• Localization: Cytoplasm
• Predicted Species: Rhesus Macaque (97%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CBR4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 25 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30459611).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for CBR4 Antibody - BSA Free

• 3-oxoacyl-[acyl-carrier-protein] reductase
• carbonic reductase 4
• carbonyl reductase 4
• carbonyl reductase family member 4
• EC 1.1.1
• EC 1.1.1.-
• EC 1.1.1.100
• FLJ14431
• Quinone reductase CBR4
• SDR45C1
• short chain dehydrogenase/reductase family 45C, member 1

Background

The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for CBR4 Antibody (NBP2-15734)(2)

Publications using NBP2-15734

• Tanie, Y, Kuboyama, T Et al. GRP78-Mediated Signaling Contributes to Axonal Growth Resulting in Motor Function Recovery in Spinal Cord-Injured Mice. Front Pharmacol 2020-06-18 [PMID: 32547396] (WB, Human)
• Tanie Y, Tanabe N, Kuboyama T, Tohda C Extracellular Neuroleukin Enhances Neuroleukin Secretion From Astrocytes and Promotes Axonal Growth in vitro and in vivo Front Pharmacol. 2018-10-29 [PMID: 30459611] (NB, Mouse)

Bioinformatics

• Gene Symbol: CBR4
• Uniprot:
  • Q8N4T8(Human)