CXCL1/GRO alpha/KC/CINC-1 Antibody (2D7)

Sandwich ELISA: CXCL1/GRO alpha/KC/CINC-1 Antibody (2D7) [H00002919-M03] - Detection limit for recombinant GST tagged CXCL1 is 1 ng/ml as a capture antibody.

Product Discontinued

CXCL1/GRO alpha/KC/CINC-1 Antibody (2D7) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CXCL1 (AAH11976, 1 a.a. ~ 107 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
• Specificity: Reacts with chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha).
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CXCL1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Sandwich ELISA
• Application Notes: This antibody is reactive against recombinant protein in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CXCL1/GRO alpha/KC/CINC-1 Antibody (2D7)

• CINC1
• CINC-1
• CXCL1
• FSP
• GRO alpha
• GRO1
• GROa
• KC
• MGSA
• MGSA-a
• MGSA-alpha
• NAP-3
• SCYB1

Background

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CXCL1/GRO alpha/KC/CINC-1 Antibody (H00002919-M03)(1)

Publication using H00002919-M03

• Cuff M, Ruzek MC, Voss JW. et al. Biomarkers for Inflammatory Disease and Methods of Using Same United States Patent Application 2016-01-07

Bioinformatics

• Gene Symbol: CXCL1
• Entrez:
  • 2919(Human)
• Uniprot:
  • AAH11976(Human)