Cytochrome P450 17A1 Antibody - BSA Free

Western Blot: Cytochrome P450 17A1 Antibody [NBP2-16077] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CYP17A1 antibody [N1C2] diluted at 1:1000.

Western Blot: Cytochrome P450 17A1 Antibody [NBP2-16077] - Sample (30 ug of whole cell lysate) A: MCF-7 7. 5% SDS PAGE gel, diluted at 1:10000.

Western Blot: Cytochrome P450 17A1 Antibody [NBP2-16077] - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CYP17A1 antibody [N1C2] diluted at 1:1000.

• Reactivity: Hu, Mu, Pm, Pm
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Cytochrome P450 17A1 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human Cytochrome P450 17A1. The exact sequence is proprietary.
• Localization: Membrane; Single-pass membrane protein
• Predicted Species: Primate (99%), Monkey (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYP17A1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:20000
• Theoretical MW: 57 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (91%), Chimpanzee (99%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for Cytochrome P450 17A1 Antibody - BSA Free

• CPT7
• CYP17
• CYP17A1
• CYPXVII
• Cytochrome P450 17A1
• cytochrome p450 XVIIA1
• cytochrome P450, family 17, subfamily A, polypeptide 1
• cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenalhyperplasia
• Cytochrome P450c17
• Cytochrome P450-C17
• EC 1.14.14.19
• EC 1.14.14.32
• EC 1.14.99
• P450C17
• P450C17CYPXVII
• S17AH

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CYP17A1
• Uniprot:
  • P05093(Human)