JNK1/JNK2 Antibody (SR1786) - BSA Free

Western Blot: JNK1/JNK2 Antibody (SR1786) [NBP3-22653] - Western blot analysis using NBP3-22653 in HeLa cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IP
• Clone: SR1786
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

JNK1/JNK2 Antibody (SR1786) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human JNK1/JNK2 (Uniprot #: P45983, P53779)
• Specificity: Detects endogenous levels of total JNK1/JNK2
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: MAPK8
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for JNK1/JNK2 Antibody (SR1786) - BSA Free

• c-Jun N-terminal kinase 1
• JNK
• JNK1
• JNK1/JNK2
• JNK1A2
• JNK21B1/2
• JNK-46
• JUN N-terminal kinase
• MAP kinase 8
• mitogen-activated protein kinase 8
• PRKM8
• SAPK1
• SAPK1C
• Stress-activated protein kinase 1
• stress-activated protein kinase 1c

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAPK8