LPAR5/LPA5/GPR92 Antibody - BSA Free

Immunohistochemistry-Paraffin: LPAR5/LPA5/GPR92 Antibody [NLS426] - Brain, Alzheimer's disease senile plaque

Immunohistochemistry-Paraffin: LPAR5/LPA5/GPR92 Antibody [NLS426] - Analysis of Testis tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: LPAR5/LPA5/GPR92 Antibody [NLS426] - Brain, glioblastoma

Immunohistochemistry-Paraffin: LPAR5/LPA5/GPR92 Antibody [NLS426] - Brain, Cortex, Neuron

• Reactivity: Hu, Mu, Bt, Pm
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

LPAR5/LPA5/GPR92 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human LPAR5/LPA5/GPR92.
• Epitope: 3rd cytoplasmic domain
• Specificity: Human LPAR5/LPA5/GPR92. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Bat (95%), Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LPAR5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1 - 5 ug/ml
• Application Notes: Use in ICC/IF reported in scientific literature (PMID: 18308941)..

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Rat (89%), Canine (89%), Rabbit (89%), Porcine (89%), Opossum (89%), Monkey (84%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for LPAR5/LPA5/GPR92 Antibody - BSA Free

• G protein-coupled receptor 92
• GPR92
• GPR92G-protein coupled receptor 92
• GPR93
• GPR93G-protein coupled receptor 93
• KPG_010
• LPA receptor 5
• LPA5
• LPA5LPA-5
• LPAR5
• lysophosphatidic acid receptor 5

Background

GPR92/GPR93 is an Orphan-A GPCR with an unknown ligand. GPR92/GPR93 has been reported to be absent from several brain regions. ESTs for GPR92 have been isolated from human normal brain, testis, and tonsil B-cell libraries and from a human blood cancer cell library (pre-B cell).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LPAR5/LPA5/GPR92 Antibody (NLS426)(1)

Publication using NLS426

• Dottori M, Leung J, Turnley AM et al. Lysophosphatidic acid inhibits neuronal differentiation of neural stem/progenitor cells derived from human embryonic stem cells. Stem Cells. 2008-05-01 [PMID: 18308941] (ICC/IF, Human)
  
  Details:
  IF (neural stem cells derived from human embroynic stem cells), Figs. 1k, 6A,B (GPR92/GPR93 was used to idenifty LPA receptors).

Bioinformatics

• Gene Symbol: LPAR5
• Entrez:
  • 57121(Human)