Transglutaminase 1/TGM1 Antibody - Azide and BSA Free

Western Blot: Transglutaminase 1/TGM1 Antibody [H00007051-B02P] - Analysis of TGM1 expression in transfected 293T cell line by TGM1 polyclonal antibody. Lane 1: TGM1 transfected lysate(89.87 KDa). Lane 2: Non-transfected lysate.

Immunohistochemistry-Paraffin: Transglutaminase 1/TGM1 Antibody [H00007051-B02P] - Analysis of purified antibody to TGM1 on formalin-fixed paraffin-embedded human uterine cervix. (antibody concentration 3 ug/ml)

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Transglutaminase 1/TGM1 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: TGM1 (AAH34699, 1 a.a. - 817 a.a.) full-length human protein. MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPDGRSRRGGGRSFWARCCGCCSCRNAADDDWGPEPSDSRGRGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA
• Specificity: TGM1 - transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: TGM1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control. It has been used for IHC-P.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Transglutaminase 1/TGM1 Antibody - Azide and BSA Free

• Epidermal TGase
• ICR2
• KTG
• LI
• LI1
• LI1EC 2.3.2.13
• protein-glutamine gamma-glutamyltransferase K
• protein-glutamine-gamma-glutamyltransferase)
• TG(K)
• TGASE
• TGase-1
• TGK
• TGKTGase K
• TGM1
• transglutaminase 1 (K polypeptide epidermal type I
• Transglutaminase 1
• Transglutaminase K
• transglutaminase, keratinocyte
• transglutaminase-1

Background

The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Transglutaminase 1/TGM1 Antibody (H00007051-B02P)(1)

Publication using H00007051-B02P

• Shimada K, Ochiai T, Hasegawa H. et al. Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus. J Int Med Res 2018-09-13 [PMID: 30213231]

Bioinformatics

• Gene Symbol: TGM1
• Entrez:
  • 7051(Human)
• Uniprot:
  • AAH34699(Human)