Calcitonin Antibody (SP17)

Immunohistochemistry-Paraffin: Calcitonin Antibody (SP17) [NBP2-26483] - Formalin fixed paraffin embedded human thyroid medullary carcinoma stained with Calcitonin antibody (NBP2-26483).

Immunohistochemistry-Paraffin: Calcitonin Antibody (SP17) [NBP2-26483] - Human Pituitary.

Immunohistochemistry-Paraffin: Calcitonin Antibody (SP17) [NBP2-26483] - Human Lung Adenocarcinoma.

• Reactivity: Hu
• Applications: IHC
• Clone: SP17
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

Calcitonin Antibody (SP17) Summary

• Immunogen: Synthetic human calcitonin 1-32 amino acid peptide.
• Localization: Cytoplasmic
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CALCA
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:25-1:50
  • Immunohistochemistry-Paraffin 1:25-1:50
• Application Notes: IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30-60 min at RT.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: Tissue culture supernatant
• Preservative: 0.05% Sodium Azide
• Purity: Tissue culture supernatant

Alternate Names for Calcitonin Antibody (SP17)

• ATP2B2plasma membrane calcium ATPase
• ATPase, Ca++ transporting, plasma membrane 4
• CALC1
• CALCA
• Calcitonin
• DKFZp686G08106
• DKFZp686M088
• EC 3.6.3
• EC 3.6.3.8
• Katacalcin
• Matrix-remodeling-associated protein 1
• matrix-remodelling associated 1
• MXRA1
• PCT
• Plasma membrane calcium ATPase isoform 4
• Plasma membrane calcium pump isoform 4
• plasma membrane calcium pump
• plasma membrane calcium-transporting ATPase 4
• PMCA4b
• PMCA4PMCA4x
• sarcolemmal calcium pump

Background

Principal Names: Calcitonin/calcitonin-related polypeptide, alpha Official Gene Symbol: CALCA Gene ID: 796 (Human) Gene Map Locus: 11p15.2-p15.1 (Human). Calcitonins (CTs) are a group of polypeptide hormones containing 32 amino acid residues which share an amino terminal ring structure, with cysteines at 1 and 7 linked by a disulfide bridge, as well as a carboxy terminal prolinamide. It is usually synthesized in the parafollicular or C cells in the thyroid gland, and also in a wide variety of other tissues, including the lung and intestinal tract. It plays an active role in calcium homeostasis. A large number of diseases are associated with abnormally increased or decreased levels of calcitonin. Alternative RNA processing of human calcitonin/ calcitonin gene-related peptide (CGRP) gene generates two mRNAs encoding the precursors of calcitonin and CGRP. It is used in the treatment of bone loss disorders because it inhibits osteoclast function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CALCA
• Entrez:
  • 796(Human)
• Uniprot:
  • P01258()