Pirin Antibody - BSA Free

Western Blot: Pirin Antibody [NBP1-87500] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

Western Blot: Pirin Antibody [NBP1-87500] - Analysis in human cell line SK-MEL-30.

• Reactivity: Hu, Rt, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Pirin Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: TVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNLRSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDF
• Predicted Species: Mouse (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PIR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.04-0.4 ug/ml
• Control Peptide:

  Pirin Protein (NBP1-87500PEP)

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23374458)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Pirin Antibody - BSA Free

• EC 1.13.11.24
• pirin (iron-binding nuclear protein)
• pirin
• Probable quercetin 2,3-dioxygenase PIR
• Probable quercetinase

Background

Pirin encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Pirin Antibody (NBP1-87500)(1)

Publication using NBP1-87500

• Shubbar E, Helou K, Kovacs A et al. High levels of gamma-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer. BMC Cancer 2013-02-01 [PMID: 23374458]

Bioinformatics

• Gene Symbol: PIR